Good-bye dear Maitikoulou

November 5th, 2009 by raghuv

Dear Maitikoulou,

It is good to have been with you. After 4 months serving with MSF in your small village, I leave with a deep sense of satisfaction. There were sure tough times. I fell sick a lot which is unlike me. The isolation was challenging to cope with as well – I live in Toronto which has about 4 million people – that is the population of the entire country of CAR.

In Maitikoulou, since it is a start-up project still stabilizing itself, the living and working conditions were rough. We all felt under a lot of stress, but we still had fun like some nights when we had a “Maitikoulou dance party” and all danced together to our favorite music. The team and I, we did our best. By no means was our work perfect. But we gave it our all and we definitely advanced you Maitikoulou from a start-up project to a functioning project.

There is still a lot more work in Maitikoulou for MSF to do. We need to finish building our in-patient ward, and we need to improve hygiene in the wards (which is critical for our malnourished patients in particular). We also need to screen more villages for sleeping sickness and put in place a computer system for managing the data of our patients who are screened and treated for sleeping sickness. This is just the tip of the iceberg. This will be the work of future MSF teams to come.

Dear Maitikoulou, despite all the challenges, we did save a lot of lives and we did alleviate much suffering. I recently wrote about Angela, Abasse, and Rahmana. I am so happy to tell you that Angela can breathe properly again – we have almost cured her severe pneumonia. She’s a bit of a miracle my national staff colleague Dr. Placide and I agreed. The two malnourished children Abasse and Rahmana are also now stabilized and both are gaining weight – I no longer fear for their lives being lost. They’re little miracles too. But with the cure of these patients, as always, come other sick patients. Treasure is a little boy just admitted with 20% second degree burns to his body after falling in hot oil. We can only do his dressing changes after sedating him with ketamine. His father fainted the first day we sedated Treasure and took off the bandages his family has applied 2 days before. I felt faint too. The sight, smell and heat that day was hard to bear. I leaned up against a bed to prop myself up as four of us worked on Treasure, hoping I too would not have to leave the room or lie down on the ground.

As is often the case, the hospital tents in Maitikoulou are full – we took out the last mattresses from the logistical stock on Nov. 1 in order to give patients a place to lie down. Malaria, infections, sleeping sickness, malnutrition and many other pathologies fill our wards. And this, dear Maitikoulou is only the end of the rainy season. When the dry season hits us, and the rivers go down, so many more Centraafricans and Chadians will present to our facility that I am not sure where the patients will go. But we’ll figure it out. The new in patient ward will hopefully be done by then and dear Maitikoulou, you will be a well-oiled MSF machine ready to ramp up our patient numbers.

Maitikoulou, take good care of those I have left behind to work in the sub-base. Take care of all the national staff and expats. Especially take care of the new doctor from Austria who arrived on Nov. 1 to replace me and the American nurse-practitioner that I worked with side-by-side, everyday, 7 days a week.

Yesterday, we did a long hospital patient round and my replacement, over a 24 hour hand-over, got a crash course on the challenges and opportunities of being an MSF volunteer in Maitikoulou. What a great feeling is to know that whereas my mission served a few specific purposes – to stabilize the medical program and advance the sleeping sickness effort – my successor’s strengths which are different than mine, will take you, Maitikoulou, in a yet more improved direction.

Maitikoulou, you took a toll on me. Sometimes, you made me wonder if I was tough enough to be an MSF doctor and volunteer. You shook me, physically, emotionally and psychologically. You lead me to do things
I don’t usually do. I said many a prayer when I felt things seemed out of my control and I even had a few cigarettes when I looked for ways to chill out and calm down. After a weekend of being really sick I told our expat nurse I wouldn’t smoke anymore if somehow I could regain my health. Maitikoulou, you made me so sick sometimes I wished I had never left Canada. And also, you made me feel so good when we cured children like Angela, Abasse, and Rahmana that would have died otherwise. So many mixed feelings. So MSF.

In the end, the best feeling is when the MSF car pulled out of the compound yesterday and we drove to Markounda, our base station. Dr. Tanja who replaced me and Dr. Martins, my medical coordinator asked me
how I felt. I said I was not happy to go, and I was not sad either. Rather, I was satisfied. Satisfied that MSF was here, and satisfied that I could be part of our work in Maitikoulou.

Dear Maitikoulou, thanks for the memories and the sense of profound satisfaction I will carry with me always.

Warm wishes from the Central African Republic,
Raghu Venugopal

A girl who couldn’t breathe and two starving boys

October 30th, 2009 by raghuv

As I am about to complete my mission this weekend and this blog, I thought I would finish where it always should start and end – the situation and struggle of our patients. Three seriously ill patients in the in-patient service here in Maitikoulou are Abasse, Angela and Ramana. Let me tell you
about the struggle for life of these three small children.

Ramana is a 1 year old boy from Chad, and slowly but surely, his life was saved by MSF. He arrived 32 days ago in a severely emaciated state. He was so weak and malnourished that he could not even cry. He could not sit up. He could barely feed so we initially fed him by nasogastric tube. I felt on
pins and needles, doing everything possible, to keep him alive and checking on him 4-5 times per day and carefully adjusting his medications and feedings.  To be honest, Ramana has not really gained too much weight here so far. But, his clinical condition has improved dramatically and slowly but surely he is consistently now gaining weight. He can now sit up, look me in the eye and put food in his mouth. Probably in 4 weeks he will reach a weight appropriate for his age. No rush. I will be handing his case over to the new doctor who arrives today. I am sure she will cure him.

Right across from Ramana is Abasse from southern Chad. Abasse also makes me feel on pins and needles. He is very sick, and so I am constantly nervous and worried about him. I check and re-check him all the time. I can’t count the number of times I saw him today amidst getting our base ready for 5 expatriates who will arrive today. Just like Ramana, Abasse is severely malnrourished. He also presented with severe anemia due to malaria and when he arrived we had to perform an emergency blood transfusion in the middle of the night. Abasse is supposed to weight 8.6 kilograms but amazingly, only weighs 4.5 kilograms. His skin hangs on him in loose, dry folds. He can barely voice a protest when I look in his mouth infected by candida fungus and check his tearless, dry eyelids for signs of anemia. But finally, his diarrhea, vomiting and fevers have started to slow down today and he is wanting to eat. Dr. Placide – the other doctor here – and I have conferred many times on Abasse and we’ve given him everything we’ve got here in the middle of nowhere. We also both think Abasse is maybe going to live if we can get him through a few more rough days. I’m leaving here in 3 days and I think I’ll know by then if Abasse will make it. It will be a busy weekend with handing-over to the new doctor, but Abasse will command my attention nonetheless.

Angela is a 1 year old female infant from CAR. She has the worst case of bilateral pneumonia I have seen here during my 4 month mission. Respiratory illnesses need to be taken seriously in this region with such a jarring lack of social services. Children do not routinely receive life-saving vaccines,
malnutrition robs their bodies of a competent immune system, and families who live far away from us wait-out illnesses such that they arrive often when a child is just about to die.

When Angela arrived yesterday, she was breathing somewhere between 60-70 times/minute – every muscle in her body was probably doing something to help her just breathe. Her lungs sounded just horrible. Dr. Placide and I both shook our heads in amazement and worry after we examined and resuscitated her together. Angela could not breast-feed and lay limp in her grand-mother’s arms. We hit her with all medications we had here to treat her. I kept checking and re-checking her, and adjusting her fluids, inhaled medications and treating her with two potent antibiotics. Slowly, over the last 24 hours, Angela has started to turn the corner. She’s getting better and not worse – she can now breast-feed – a good sign that the effort to breathe is not the only thing she can do at once. It is great to see. I’m very hopeful she will live, and I want to see her really turn the corner before I leave. We’ll truly know in 3 days if she is on the road to recovery. My fingers are crossed and we will do our best.

Warm wishes from the Central African Republic,
Raghu Venugopal

Hortence and her 17 pieces of nifurtimox

October 29th, 2009 by raghuv

Here in CAR the mission is now without nifurtimox. As I wrote about before, it is one of the key medications to treat sleeping sickness. We need this essential medication for this neglected disease.

Hortence, a 10 year old girl, with the severe cerebral form of the disease needed just 1 ½ pills, twice, in order to complete her treatment. You’ll perhaps remember in previous blogs I was forced into prescribing her the far more uncomfortable 14 day regimen of intravenous eflornithine because of MSF’s rupture of nifurtimox.

Luckily though, on Sunday, when I was filling in for the pharmacist on his day off, I found an empty bottle of nifurtimox. Whimsically, I shook it. The rattle of a few pills caught my interest and hope. I opened it. Inside were small pieces of nifurtimox – 17 in total. I found a clean piece of cotton gauze and carefully put the shards of nifurtimox together. I stared long at them and went over to Cyriaque – one of our nurses. I asked him if he agreed there were enough pieces to make up 3 pills. He agreed – definitely he said. I felt better and knew we were doing the right thing. We evenly divided up the shards in two small pill bags and then next day, after receiving the 2 doses of 17 pieces of nifurtimox, Hortence went home.

This was a good ending to what could have been a difficult 2 weeks for Hortence. It was also a sad and frustrating commentary that we are reduced in this mission to piecing together shards of pills for a wholly treatable and eventually fatal disease. Now that the shards are gone, everyone will need 2 weeks of intravenous eflornithine – 4 times a day – and that will be difficult for many of our patients.

Warm wishes from the Central African Republic,
Raghu Venugopal

Hortence needs 1 tablet of nifurtimox

October 27th, 2009 by raghuv

A complicated story which I can best tell from the simple perspective of taking care of the patients is the need for MSF to obtain the right drugs in the right quantities at the right time. It is an important struggle being waged by many in MSF at levels far beyond this little village.

One of the key medications in treating sleeping sickness is called nifurtimox, and we ruptured in this medication yesterday. We knew the day would come when we would run out of this medication, but it did not make it easier.

Two months ago we realized our stock of nifurtimox had a limited shelf life of only until the last day of October. And as a result, we decided to stop prescribing it on October 21. This would ensure none of our patients would receive any expired medication, when it expired on October 31, since once we start a patient on treatment they need it for 10 days. But that also meant we needed to use up our remaining stock so this valuable medication which reduces the number of painful intravenous eflornithine infusions from 48 to 14 was not left to expire without use. So we put as many patients as we could on this approved combination chemotherapy of both eflornithine and nifurtimox, balancing trying to use up our stock before it expires, and also trying to reserve it for children who are difficult to find veins on to start intravenous lines.

Hortence is one of many patients who will be impacted by our nifurtimox rupture. It is a sad story in her case since she needed just 1 more pill. Really. Just 1 more pill.

Hortence is a 10 year old girl from a village about 25 kilometers from Maitikoulou. She presented to us with advanced stage 2 sleeping sickness 10 days ago. Her sleeping sickness had entered her brain and central nervous system. Although her mother says Hortence was treated for a milder form of the disease in April 2009, we initially could not find her in our computer records. Eventually, we figured out that a different name was probably given to us during Hortence’s previous treatment, and confirmed her mother’s insistence that Hortence had been treated by us for sleeping sickness.

When Hortence arrived this time, she could not walk and she could not talk. The out-patient staff brought this to the attention of our American expatriate nurse, and we again performed Hortence’s lab tests, including a spinal tap. Hortence had a very high white blood cell count in her cerebrospinal fluid, and tested negative for meningitis, indicating to us that she had the more advanced form of sleeping sickness.

Hortence has done great. But she’s not cured. After the past 9 days of treatment with intravenous eflornithine twice a day and oral nifurtimox three times a day, Hortence has made a very good recovery. This morning I watched her walk. She took slow, steady steps, but was able to do it. She is also talking a lot more than before. Her family is happy with the progress, and the medical team is as well.

But we ran out of nifurtimox. And Hortence needed just 1 pill. She needed half a pill last night and half a pill this morning, and then she could go home and follow up with us. No more needles, no more painful intravenous treatments ₋ that was the plan. I can’t conscionably cut her – or any patient’s chemotherapy short – even if it is one pill. The implications of failing to properly treat this fatal disease are just too great. Heaven forbid, if we don’t treat patients precisely according to protocol, they could develop sleeping sickness and die, or develop the disease and need to be treated with one of our second-line drugs, melarsoprol. This latter treatment, melarsoprol, is known to have horrific side effects and kill many patients. So you can see how nit-picky we have to be that every patient precisely undergoes an approved therapy. No exceptions.

It came to my attention on a Saturday afternoon that we had a nifurtimox rupture because the nurses’ aides could not find any nifurtimox to give the 11 patients we had who were receiving this medication. I was surprised to hear the pharmacist had “forgotten” to distribute this medication and opened the pharmacy myself to see what was going on, long after our staff had left. And indeed, there was no nifurtimox on the shelves. OK, next step – got to talk to Simon our logistician-team leader and ask him to do what we rarely do now, which is open the medical stock to get more of this medication. But Simon confirmed my fear – he had given out the last two bottles of nifurtimox over a week ago. He said we were totally ruptured. Darn. I thought to myself ₋ what are we supposed to do with those patients already under treatment? The answer. Treat them all over again with just the intravenous medication eflornithine, but this time, use the approved protocol reserved for monotherapy of eflornithine.

So we are now retreating 11 patients who could have gone home after just 14 intravenous infusions, but now need 48 infusions of eflornithine over 14 additional days. No matter how hard we try, it will hurt their arms, they will suffer side effects, many will need more than a few painful needle pokes. It is one thing for an adult to go through this, but for the 1 year old child and the other 4 year old child on the ward, it will be especially hard.

MSF’s Campaign for Access to Essential Medications has published online documents detailing the history and future of our struggle to get medications like eflornithine and nifurtimox to the field. Further, at the capital and international levels in this mission to CAR, I know the medical, logistical and humanitarian affairs teams at MSF are working hard to get more nifurtimox for Maitikoulou. I know, because I push them. I tell them what I tell you ₋ that life will be hard for our patients receiving 48 eflornithine infusions rather than just 14 eflornithine infusions when we are able to combine it with 10 days of oral nifurtimox.

For now, there is no nifurtimox available in the Central African Republic, to treat this rare and neglected disease. We will administer instead these painful eflornithine infusions with a number of side effects and complications, always knowing there is something better and easier out there. I will push MSF, and MSF will push others including governments, drug companies and international health agencies to put the drugs in our hands. If we succeed in this goal, 10 year old girls like Hortence can go home to their villages faster and easier, which is where they belong.

Warm wishes from the Central African Republic,
Raghu Venugopal

An end in sight

October 24th, 2009 by raghuv

The end of my mission is soon at hand. One week to go. I will not miss the horrible smell of plastic and medical waste burning just beside our office. I will not miss the piercing daily sound of children crying as they receive their sleeping sickness medications. I will not miss the never-ending, relentless drone of the diesel generator twice a day, everyday. I will miss long walks in the woods along a tiny rural road. I will miss that feeling of taking off in the Red Cross plane. Fellow MSFers know it well – once in the air – with some distance between you and this work – you realize it was worth it all.

Thankfully, MSF has found a good replacement for me. An experienced doctor from Austria, with many missions under her belt, will take my place. I have been in contact by email with this new doctor in the past couple of weeks. I’ve sent her reports, emails and other key documents to give her a chance to come to Maitikoulou aware of the challenges and the opportunities. It is a good feeling to know experienced hands are following you.

No doubt there will be changes made by my replacement to the system that we’ve set up now to care for sleeping sickness and other patients. But that’s good. A fresh set of eyes and new energy is always important in MSF. As for me, I’m tired, I’m looking to go home, I have done all I can. I have done my imperfect best.

There is a lot of change in the air in this bustling sub-base. Finally, a better expat compound is taking shape. Thank goodness the new expats will have better living and working conditions than we have seen here so far.  Maybe in a week, logistics will have finished the common area and the kitchen. I wish it had been there for me to enjoy earlier. It would have made the mission a lot easier. The foundations for a real in-patient facility are also laid, and they’re building the walls now. It’s gorgeous. It’ll sure beat doing patient care out of our urine-smelling, musty tents. You drop your pen in the tents right now and you wash your hands a few extra minutes at the end of the round.

And the medical work, it goes on. Lots of malnutrition, malaria, childhood sepsis, skin and soft tissue infections, traumatic injuries and respiratory illness cases fill the tents. Today I did a training for the staff on the approach to a patient with convulsions, as that is a common and serious problem here. The staff loves any opportunity to learn and interact. At the end of the training, Timothy, one of our nurses’ aides asked if I could spare a notebook so he could keep better notes. I’ll have to check on that one – maybe we have some small notebooks to spare somewhere in the stock.

Simon our logistician is signing-off on Monday. He’s finished his mission after 5 tough months. He has worked hard and long (very often 7 days a week), and today was his last meeting as our team-leader. I gave a long speech to thank him, but also give a thankful nod to the whole logistics team that works with him. The logistics and administration teams in MSF make practicing medicine possible here, in the middle of nowhere in this central African country. It takes a lot more than doctors to deliver good medicine.

I took a long walk to finish today. Usually I take walks with Kathryn, the American nurse, but she’s at our base this weekend. It had rained and the air was cool and fresh. One the way back I saw a man walking very slowly, shuffling and wondered what he was up to. As I passed the man, I recognized it was our staff Timothy who was reading what looked like a letter from a far-off relative. I asked him what he was reading. To my surprise, it was the notes he had taken today during the training on convulsions. Hmm, I thought to myself. That sure makes you feel like the effort was worth it that someone would re-read the notes they had taken alone on a lonely small country road in the middle of nowhere, here.

Warm wishes from the Central African Republic,
Raghu Venugopal

Remarko comes to the HAT camp

October 13th, 2009 by MSF Field Blog

I am now in the 4th and last month of my mission in Maitikoulou. Certain truths have unfolded. The MSF Land Cruiser side-door mirrors are the best to shave with. There is little point in trying to sleep once the sun starts to rise around 5:30 AM, unless you go to bed too late. I’m always going to be sick.

Sunday morning shave in the Land Cruiser mirror

Sunday morning shave in the Land Cruiser mirror

Other truths to me include that the living conditions here at this HAT camp will always be to my personal disliking. There is little space for personal privacy. I can rarely stop being a doctor or an MSF volunteer.

At home in Toronto, Canada – when I am done work at the hospital, I can easily be absorbed by the crowd on the street when I exit the hospital. I cannot do that here. You’re always a bit of a novelty here. Going for a walk after work is like being an animal in a zoo – on display. And lastly, the strong will survive – this is Darwin’s domain. The weak can maybe survive – but the odds are largely stacked against their survival. But there are exceptions. Exceptions are important – they are a window for a different future for the weak and poor in my opinion.

As a case in point for this last observation I would like to tell you about Remarko. Remarko is a crippled man. Both his legs are atrophied and almost useless. This is likely due to polio when he was a child.

Remarko is indeed true to his name – he is remarkable. He moves himself all around using only his arms to carry his body. When the distance he must cover is a longer one, he holds onto one leg (which he can straighten) and then rolls from his front to his back. His progress is slow but it seems determined. His blue and red soccer jersey is covered in dirt most of the time, and he does not travel too far. His life is tough but he still has a shy smile and certain resigned happiness to his personality.

The other crippled man who also carries himself by his hands is a well-known person around Maitikoulou village. We sat beside each other once in the Protestant Church where I go to enjoy the singing. I don’t know this man’s name but he also always smiles widely and waves hello. He seems to still be engaged in life despite his obvious serious disability. Neither of these men ever ask me for anything.

I always give the patients the plastic empty bottles that once had medications. In addition to empty boxes and empty bottles that once held peanuts, the patients love these as they are clean and they can put water or other things in them. People are very poor here – everything is recycled. I’m not worried about the bottles being laced with medication as the medications are put in a bag before being placed in the bottles. When empty containers appear, I usually evenly distribute them, tent by tent.

This time, I gave two big and one small medication containers to Remarko. He seems surprised but happy. He kept them on his bed.

Remarko has no guarde de malade – no one is there to take care of him. This is odd, since a guarde de malade is the rule here. No one – really, no one – comes to hospital without someone else there to help feed, tend, bathe and advocate for the patient. This is markedly different than medicine in Canada were I frequently attended to patients who are alone.

I think being crippled and with no guarde de malade is why the other villagers in Remarko’s tent took his 2 large bottles and left him the one small one. When I asked those in his tent where his bottles went, two strong healthy-looking men also being treated for sleeping sickness pulled them from their bags. I scolded them. But this is Darwin’s domain – the strong survive. But there are exceptions.

After this incident, I decided to make a little care package for Remarko – in private. I have been secretly keeping some boxes and bottles I know him and his sleeping-sickness affected family will be happy to use for this and that. But I keep it in our medical office as I know the strong will take from the weak. When Remarko returns home in the MSF Land Cruiser I will make sure these little things go with him.

Remarko’s life has been hard lately. His mother also had sleeping sickness and was treated here. She is quite old and is in failing health. I recently brought her by Land Cruiser to the hospital for some tests and additional treatment. There is honestly not much I can do for her chronic ailments here – other than treating her severe arthritis and testing her for parasites and malaria – we have little other diagnostic capabilities here. Stating he was worried about his mother, Remarko initially did not want to come to hospital to be treated for sleeping sickness. A long talk with him with the help of his village chief, changed his mind. As well, his village chief agreed to come and be Remarko’s guarde de malade for a day. That must have helped as well.

As an MSF medical doctor in this community, I believe I enjoy a position of earned respect. I am aware that how I talk, how I treat people (including even the most simple interactions), and how I conduct myself can set the tone for the team around me, for good or for ill. I am hopeful that if I try to protect the weak, show genuine empathy and compassion for as many as I can, and act fairly and justly I can positively influence those around me. I think this is an important part of being an MSF volunteer and of being a medical doctor.

Warm wishes from the Central African Republic,
Raghu Venugopal

Four emergency transfers and five lives (Part Two)

October 12th, 2009 by raghuv

Correction: in blog 19 I described 4 emergency transfers with five lives at stake. Sadly, I learned today that one of these patients died yesterday on October 11. And thus, three out of our five patients who were emergently transferred in the last week lived.  Two patients died – one a newborn and the second death was our 4th transfer, a patient named Souh. I will tell you about Souh, below.

Note: all patient names have been changed or shortened to protect confidentiality.

“At one point during one of our meetings the minister [of foreign affairs for Sudan] had expressed his fascination with “you MSF fellows and ladies. Why do you do it” he asked. I replied immediately, “Because we can”.”

-James Orbinski, “An Imperfect Offering”

Because “we can” is an important reason why I am an MSF volunteer. We can save lives, we can alleviate suffering and we can help restore dignity of those living in danger. It is within our grasp. It is possible. We have doctors, nurses, surgeons, drugs and equipment, logistics, coordinators, radios and Land Cruisers. We are willing and ready to operate in places others are not willing to be present. We take calculated risks to our own personal safety and well-being to be here. We realize our endeavor is not perfect, but nonetheless we are in constant pursuit of improved professional and compassionate medical care. Because we can.

Case three: Thursday October 8, 14:00 PM

Simon my team-leader and I were back on the road to Maitikoulou after transferring our patient Felicite to Markounda (and then Boguila) for emergency surgery. We were tired but satisfied things had gone smoothly. We had got to spend a night and morning in Markounda, which for me is paradise  compared to Maitikoulou. I was scanning some MSF radio channels (Spain and France) in complete boredom in the 2nd MSF car in our convoy.  Simon’s car stopped ahead of us. He got out and asked me if I had heard all the talk over the high-frequency radio about a sick MSF staff member. I had not. I felt a bit embarrassed I had been fooling around and not heard the call. My bad.

It turned out there was a concern regarding an MSF staff member with a possible stroke. I immediately knew who it must have been – Sara – one of our female nurses I had been attending to for the past 2 days with a severe, but resolving headache. This MSF nurse’s headache was not classic for an aneurysm which had leaked or ruptured in that it was not the worst of her life and did not develop suddenly like a bolt of lightning (but unfortunately as well, most ruptured aneurysms don’t present “classically” – classic medical presentations are for textbooks and do always occur in real life). But it was a bad headache. I had treated her for malaria, sinusitis and a migraine headache, but the thought of a ruptured aneurysm lingered in the back of my mind.

When I first encountered this nurse, I seriously thought about medically evacuating her, but since she rapidly and consistently improved each time I visited her in her, I thought we could monitor her improvement in our project. Plus, you cannot evacuate everyone who falls sick – it just occurs too frequently that someone falls sick and the vast majority get better. Just before I evacuated Irene, I had visited Sara, our sick nurse. Sara was getting better, eating and having less pain.

On the road at Mainojo health clinic, Simon and I called our medical coordinator on the Thuraya satellite phone. My suspicion that it was Sara who was sick was unfortunately correct. She had fallen unconscious on Friday October 9 at 13:00 in the afternoon. Our American expat nurse-practitioner Kathryn had already gotten approval from the capital to begin evacuating Sara out of Maitikoulou. Sara was having seizures and could not be aroused. Simon and I quickly made plans for me to take one MSF car and evacuate Sara to Markounda, where we could hopefully fly her out on the first flight possible. This would mean I could not return to Maitikoulou as planned.

When Kathryn brought Sara by car, the diagnosis was correct. Sara was in a comatose state. I rubbed my knuckles deep into her sternum but there was no response. We hastily changed staff and kept Sara in the same car. With Papa Eli – our best driver – we drove like hell to Markounda. Collete, one of our national staff nurses sat in the back of the car with Sara. She softly sang. Papa Eli – who is also a pastor with the Catholic Church prayed and asked for blessings as he drove as fast as he could without endangering us or bystanders. We reached Markounda and I immediately examined Sara. She was completely paralyzed on the right side of her body and the left side of her face, and could not speak. I phoned the medical coordinator in the capital city and he informed me that he had arranged an air evacuation on a United Nations plane the next morning. I thanked the medical coordinator Martins for his fast action.

The night for Sara passed smoothly and without incident. The MSF national staff were obviously very concerned and one of our employees openly thanked us for taking care of the national staff so seriously. In the morning, Sara’s flight departed without incident to the capital. We had lost from our project a fantastic bedside nurse, a trusted colleague and a friend.

Lindsay our American log and I got back to the base. I felt nauseated, guzzled a liter of water and organized a second doctor’s rounds in the inpatient ward. The first round in the morning was rushed due to the need for Dr. Honore, our local national staff doctor in Markounda, to prepare to take Sara on the plane. Him and I did a quick tour so I could find out who was really sick or complicated.

As I headed to the ward, Lindsay announced that believe it or not, there was an emergency transfer request from Maitikoulou.

Case four: Saturday Oct. 10, 11:30 AM

Souh, age 45 from southern Chad arrived in Maitikoulou the night before. He had severe abdominal pain, fever, and vomiting. His abdomen was bloated and with clear signs of peritonitis. Peritonitis indicated that his intestines had ruptured somewhere and fecal matter was inside his usually sterile abdomen, causing an intense and excruciatingly painful inflammatory reaction. Kathryn, our clinically sharp nurse-practitioner and I talked on the satellite phone. She was 100% convinced this man needed surgery, and I 100% believed her based on my experience of her spot-on clinical ability.

I called the medical coordinator in the capital – he approved the transfer. Then logistics arranged the transfer. Frank, our German project coordinator here in Markounda approved the movement, and Lindsay the American logistician drove out to meet the Maitikoulou MSF cars. She radioed me as she approached. The patient wanted to sit up and she wondered if that was OK. I told her let the patient do whatever he wants in order to get comfortable.

The MSF coordination team in Bangui was not in favour of moving the patient all the way to our surgical site in Boguila. They had security concerns. They advised that I make a quick decision when Souh arrived whether I could stabilize him here in Markounda or if he truly had to be moved out right away to Boguila. Good copy – I could do that.

When Souh arrived he looked terrible. I got 6 other men and we carried Souh out of the car to the reanimation room. He had no blood pressure. I could not feel his radial or his carotid pulse. His respirations were labored and far too fast. I quickly hung two bags of intravenous fluid to try and boost his blood pressure. I listened to his abdomen with my stethoscope – no bowel sounds – a bad sign. His skin was oven hot and his abdomen was bloated and excruciatingly tender to the lightest touch. I gave Souh an antispasmotic medication, a pain killer and medication to stop vomiting. I told the men to get him back in the car right away. I ran off to find Frank and tell him Souh had to go.

Frank and I called the medical coordinator in the capital again. I told him Souh will die if he stays here overnight. The movement to Boguila was  approved. Once more, I told Lindsay the logistician to just drive like hell, bumps or no bumps in the road.

Lindsay got back to Markounda on Sunday afternoon October 12. She had bad news. Souh had died. The Boguila team had taken Souh to the operating theatre, where they found a ruptured appendix. Afterwards the patient did poorly and despite aggressive attempts to keep him alive with potent medications to raise his blood pressure, it did not work.

We all agreed the attempt to save Souh’s life was unquestionably worth it. What efforts we made exist in a complete vacuum of any other actors to try and help this man. Sadly enough, we were his only chance.

And why do we do it? Because we can.

Warm wishes from the Central African Republic,
Raghu Venugopal

Four emergency transfers and five live (Part 1)

October 11th, 2009 by MSF Field Blog

“Humanitarianism is about more than medical efficiency or technical competence. In its first moment, in its sacred present, humanitarianism seeks to relieve the immediacy of suffering, and most especially of suffering alone”
- James Orbinksi, “An Imperfect Offering”.

Note: all patient names have been changed to protect confidentiality

As a physician and as an MSF volunteer, I exist to serve the most ill. In emergency medicine, my specialty in Canada, this is our goal as well. The last week here in Maitikoulou has been a difficult one, with many emergency transfers, some under difficult circumstances, but all with the aim to  preserve individual human lives – for which MSF exists.

Many of our medical interventions here in CAR aim to serve the population at large at a public health level. These efforts include vaccination, mass screening for sleeping sickness, distribution of bednets, antenatal care and supporting remote health posts which are the most basic and also most accessible first line of medical care for the population of CAR. But at the same time, MSF exists to manage, case by case, the sickest patients that come to our attention on a daily basis. At the same time, us as the medical attendants, also often fall sick as occurred this week out here in the bush,  and we must care for each other.  Here, there is no health care except MSF.

Let me tell you about 4 emergency transfers in one week. Five lives were at stake and four out of five of the patients lived.  One patient died.

Case one: Saturday October 3, 8:30 AM.

Irene, age 18, had been in labour 26 hours before she came to my attention. I had just finished giving a training to the national staff on the approach to managing diarrhea. Dr. Placide, the national staff doctor, told me about Irene. It was her first pregnancy and the baby had become obstructed in the lower birth canal. Earlier, medications to augment her contractions had failed, and the child was still alive as Dr. Placide said he could hear a fetal heart rate. The mother was exhausted. I performed an ultrasound and saw the fetal heart rate was present and at a normal rate. I could not use suction to remove the child since there was too much swelling around its head. Such obstructed labours need a cesarean section – something I cannot do, much to my frustration.  At 11 AM after multiple clearances from my team leader, project coordinator and medical coordinator, we evacuate out Irene. I knew that even if the baby died we had to at some point remove the fetus from the mother or else she could face multiple complications, including death.

We had to stop many times on the road since Irene and her own mother, not accustomed to the Land Cruiser, vomited a lot. I give them both anti-emetic medications, lied them side-by-side as comfortable as possible and eventually put her mother in a care front seat. Nothing really helped. Irene cried out in pain as we tried to avoid holes in the dirt road but inevitably hit many. Each bump is like a punch to the chest when you are lying on the floor in the back of a Land Cruiser. At Dokabi, or “Delta-Kilo” as we call it, we did a “kiss” with the Markounda team MSF cars. Lindsay, a wonderful, cheerful American logistician, and Hilaire, a top-notch and gentle national staff nurse, took over the transport and care of the patient.

Two days later by email I learned Irene had receive a cesarean section and she was alive. Her baby was alive as well, but was not breast-feeding. I had Irene’s family called to the hospital and gave them the news. However, on Wednesday October 7 I had to inform Irene’s family that the baby had died but the mother was still alive.

As I write this blog I am actually at our base, in Markounda, due to other emergency transfers. Yesterday October 10 I actually found Irene in the in-patient ward here, as I was doing the patient rounds. Irene was on her way back to Maitikoulou. She lay quietly in a bed. As she speaks only M’Bai she could not communicate with anyone since no one here speaks M’Bai. They speak Sango here. She was alone as well, her own mother gone. I found Irene with a high fever and intense abdominal pain. I talked to her in my few words of M’Bai and started her on medications for an intra-abdominal infection. She is not out of the woods yet.

Case 2: Thursday October 8, 4:05 PM.

Felicite, age 24 was on the ground moaning on the steps of the out-patient department. In my experience, the Chadians and Central Africans I attend to do not lie on the dirty floor unless they are quite sick. I was exhausted after sleeping very little the night before trying to save a 2 year old boy with cerebral malaria who ended up dying after my best efforts over 3 days. I had just repaired the hand of a daily worker who suffered a partial amputation of his finger after it went into a saw. I had no energy left. I saw Felicite on the ground and the best I could honestly do was ask our national staff nurse, Hebert to attend to her, admit her and tell me if he had any concerns. Hebert is an outstanding nurse with almost military discipline and promptness. I ask him to do many things and he does them without question and with exceptional reliability.

Hebert was concerned and notified Dr. Placide, our national staff doctor. Dr. Placide in turn felt the patient had a ruptured ectopic pregnancy. When I examined Felicite it was clear she had peritonitis (a ‘surgical abdomen’) and needed immediate emergency surgery. But the time of the day was late. Too late. To confirm the diagnosis, I had the nurses insert a bladder catheter and do a urine pregnancy test. It was positive. I performed an ultrasound exam and transabdominally I could see a classic black sliver of fluid between Felicite’s kidney and liver – presumably blood from a ruptured ectopic pregnancy now bleeding into her abdominal cavity. I then did a transvaginal ultrasound exam as I have been trained to do in Canada. I could not see any evidence of a pregnancy where it is supposed to be – in the uterus.

With all the information we had at this point, a key series of events again unfolded to authorize an emergency movement of this patient to surgical care. I sweated and paced while awaiting a phone call back to hear if we would get permission to move her. Back home, within 30 minutes, she would be in an operating theatre. Here, I was potentially being asked to stabilize her for another 18 hours, which is when she would arrive at our surgical site, if a movement was only permitted the next day. I was concerned Felicite would die. A mother of 3 children and a wife.

Thankfully, permission to transfer Felicite was granted. As this was transpiring, we hastily tried to find a blood donor. Felicite was A+ – only two other blood types were possible. Unfortunately, the first two men who volunteered to give their blood tested positive for hepatitis. Thankfully, a third donor was found and his blood tested negative for any infections and we hung the blood along with multiple other medications from the roof of the Land Cruiser and started our movement to Markounda.

On the way, we passed Felicite’s village. They all lined the dirt road and blocked the passage of the cars. They wanted to exchange her husband as the guarde de malade for Felicite’s sister in law. No problem, we made the switch. Mommas and poppas looked into the car and talked to Felicite. They said things to me I could not understand. I am sure they realized with five infusion bags hanging (including one with blood) from the roof and three intravenous lines inserted in Felicite’s arms that we were doing our best to save her life. I said to them we are going to Markounda and then Boguila. I think they understood that as well. It was touching to see her whole village lining the road as we took her out.

Like all patients in pain, Felicite suffered on the long 5 hour drive. Each bump and twist, she moaned and cried out. I had not brought any pain medications in the scramble to get her loaded, transfused and treated with other medications. Jacob, a truly loving and gentle secourist, had volunteered to come on this transfer with us after working for 12 hours in the in-patient ward. I wanted him since I trusted him and he could speak M’Bai to the patient and explain to her what was happening. Each lurch and crash of the car into ruts and bumps, Jacob and I held the medication bags thrashing about in the back of the car. Jacob held the patient’s shoulders and I held her right hand. We tried to comfort her and warn her when a big bump was coming.

I was getting seriously car sick and did not need to be in the back of the car anymore to keep an eye on the patient.  I knew well she was OK since she moaned every few minutes. I moved to the front seat of the car. Along the road, armed military personnel stopped us. They quickly realized what we were doing and allowed us passage. Anyone could see we were trying our best to save someone’s life.

When we got to Markounda, I re-examined Felicite. She was still critically sick, but it was night and we could not move further due to security concerns. I arranged for a bed for Jacob beside Felicite. I was starving and ate some Plumpy Nut usually used for the malnourished children. The nurses gave me a bed in the adjacent examination room but since I am so afraid of mosquito bites I chose instead to sleep in the ward with the patients under a bednet.

At 3 AM I was woken by the crying of children and the nurses who wanted my help for a child with cerebral malaria. The 3 year old girl was dying, I knew it. It is sad but now I know well the breathing of a child who is soon going to die. They gasp and the side of their mouth opens as if you were trying to show your canine teeth to someone. I had the nurses call the local national staff doctor, Dr. Honore, who had attended to the child for 3 days. I had just been through this kind of case all night just yesterday. I started the child on antibiotics, gave diazepam and glucose to stop the seizures, and began oxygen (a useful intervention I don’t have in the bush in Maitikoulou). Dr. Honore arrived and agreed with my treatment and agreed the child would likely soon die.

The crying of the children in the ward kept me up. I need to sleep. So I took some blankets and slept on the dinner table at the old expat house, now used as a storage facility. I could have gone to the expat house and slept in a proper bed, but I was not going to leave Felicite without my constant medical attention.

At 5:15 AM the sun woke me up and I radioed Lindsay, the base logistician, and she arrived with two MSF Land Cruisers. We loaded Felicite in the car. I told Lindsay to just drive like hell out of here. Lindsay radioed me 30 minutes into her journey to our sister project, where we could do surgery. She said they forgot some medical equipment. No matter, I said, just keep driving. This woman needs a surgeon and nothing else. Felicite entered the operating theatre at about 8 AM. She survived.

This is what MSF is for.

Warm wishes from the Central African Republic,
Raghu Venugopal

David and Zo Kwe Zo

October 5th, 2009 by MSF Field Blog

Perhaps you have read before in this blog about David. He is is age 28 and has been chained to a tree for the past 6 years. I had thought his confinement was 5 years, but on my fourth visit to him under his tree, his village chief corrected me and told me it was, in fact 6 years. I believe David suffers from chronic schizophrenia. I am not using his real name here. His village has found that only by chaining his right leg to a large tree trunk can they control his behaviors and sometimes violent actions.

One of the most important historical and political figures in the Central African Republic is Barthelemy Boganda. He stood up against the former French colonialists and pushed for basic rights for the common people. It is said he coined the Sango phrase “Zo Kwe Zo”. Zo Kwe Zo translates into “every human being is a person”. When you are in the capital city Bangui, you can see this inscribed on prominent national landmarks. When I first read this saying I thought of David. Even though he is chained to a tree, he is still a person. When I am tired and frustrated and want to be left alone by the nurses and I need to dig a bit deeper this saying helps me muster more energy to take care of someone or some problem the best I can. Zo Kwe Zo. Zo Kwe Zo.

On my last visit to David, which occurred while we were nearby screening for sleeping sickness, I performed some laboratory tests with the permission of his family. I first needed to sedate him with an injection of ketamine, which worked quite well after a second dose. David entered what we call a ‘dissociative state’ under ketamine, where he did not feel pain and was not be aware of what I was doing to him. We did some blood tests and I performed a lumbar puncture. The whole village stood around and watched quietly. The village chief tried to shoo them away but there were just too many. In our previous attempt to test David for sleeping sickness 7 men and I could not restrain him enough to perform it properly.  That is why we resorted to ketamine.

While sedated, David drooled, and his copious sputum smeared the side of his face. His mother stayed beside him and used an old sack to clean him. While David was asleep his brother also brought over a pair of scissors. Quietly, he gave David a haircut. David soiled himself. His mother covered him with a rag. I asked his family to take the opportunity to bathe him since apparently, he never lets himself be washed.

The lab investigations proved David did not have sleeping sickness but he did have malaria. This is not surprising since he lives outside without a bednet. When the Anopheles mosquito looks for a blood meal at dawn and dusk he is a quite susceptible. Treating this man’s malaria will not be easy. He will not accept oral medications, so we’ll have to do it by some injectable route. The bigger question is how to prevent future malaria infections.

Maybe we can sew a few bednets together and fashion them around his tree. Hmm, I’ll have to ponder this further with help from logistics.

For David’s mental disorder, I have sought the advice of my medical coordinator in the capital city, psychiatric colleagues and those at higher levels in MSF. The case of David is complicated as there will be no easy fix, and if we start any treatment for mental illness, it will likely take some commitment on the part of MSF and other actors to see it through. Six years of severe mental illness will not be cured as easily as malaria or sleeping sickness. But at least we’re checking out the options, asking difficult questions amongst ourselves, and trying to find a better way than right now.

Zo Kwe Zo.

Warm wishes from the Central African Republic,
Raghu Venugopal

Eloise and the hunt for sleeping sickness

October 3rd, 2009 by MSF Field Blog

The pursuit of cleaning our nearby villages of sleeping sickness continues.

Last week, the mobile team and I made 2 visits to 2 local villages. We screened until no one wanted to be screened anymore. The villagers and village chief were satisfied that they had been thoroughly tested for the fatal disease. I was satisfied as well. I could personally see each visit we made to these villages yielded fewer and fewer people wanting to be screened. A good sign.

When we go to the villages for mobile activities, we pre-empt our visit by sending letters to the village chief to inform their population we will be coming. Then we send one of our staff on a bicycle to the village to discuss what is sleeping sickness and why we are coming.

Once we get to the village, it is festive. Laughing and smiling children gather by the dozens. They want to shake hands, try out some of their French and check out the excitement. Village elders are given chairs under a massive tree to calmly observe the proceedings and I assume reflect on the state of their people. Our two MSF Land Cruisers and 7-8 staff begin unloading equipment and greeting the gathered onlookers. I feel good too. I love this.

The first priority is to formally greet the village chief and ask his permission to undertake our activities. Then we have to set up a large perimeter so that innocent and curious people don’t disturb our laboratory  staff or mix up the order of people cueing to have their blood tested for the sleeping sickness parasite. Crowd control is a top priority but so is the comfort of those waiting to be tested. We try to select areas of the village where people will have some shade from the baking sun as they wait to be tested. Although right now, we can screen around 30 persons per hour, there still is big cue.

I constantly talk to the people waiting in line. I tell them why were are here, what is MSF, and what is sleeping sickness. They thank us. I answer their questions. I socialize and try out some new words I have learned in the local language, M’Bai.

My favorite activity is talking to mothers about their children. They eagerly let me hold their babies and it brings me delight. My white MSF t-shirt takes a yellow and brown colour many times as a result of holding babies. Ever since I have joined MSF and now in my second mission, nothing makes me happier than holding children with their families’permission. Justin and Jacob, two reliable and motivated national staff with us on the mobile activities love children as much as I do. They want in on the fun. They ask to hold the children I’ve plucked from the crowd. We smile and we feel good.

Eloise is a young woman with a baby who has been screened positive for sleeping sickness. When I talk to her about coming to hospital for more testing and treatment, she refuses. My usual explanations don’t seem to work. I sit with her on an uncomfortable bench made of a knotted tree trunk and ask why with the help of Felix, one of our local staff.

Eloise is a widow, she is busy, she has no soap, she has little food and she is poor. I spend 20 minutes more talking with her. I assure her she will be fed at the hospital from food donated to us from the United Nations World Food Program. The mobile team has packed up and the Land Cruisers are ready to go and the team is waiting for us. We have another village to go to. I find the village chief and see if together we can convince Eloise to come.

We are standing beside the running Land Cruisers now. She still refuses. I am vexed. What can I do to motivate her to come? In the end, it is her choice; I can only inform her of the risks and benefits of treatment and of not being treated.

Finally, I tell Eloise that if not having soap is her main concern, I will give her soap. I promise her some bars of soap, knowing we routinely give out soap anyway to the malnourished children in the hospital. It will cost us pennies if at all. Eloise agrees. She will come. I give her a handwritten note to give to me when she arrives and then I will make sure she gets soap and is taken care of.

Eloise is symbolic to me of the plight of Centraafricans in this region. Jarringly poor, with practical concerns, needing basic things like soap, clean water and basic medical care from potentially fatal diseases.

Onto the next village.

Warm wishes from the Central African Republic, Raghu Venugopal